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2012年1月17日星期二

Local band seeks to win contest, make it to SXSW

Guitarist Duncan Kissinger said that Hotfox is a band that advocates the importance of utilizing the full buffalo when it is hunted.

“Some people just use it for meat, some use it just for the pelt. Use all of it, not some of it,” Kissinger said.

Even though the band wouldn’t fully reveal what the buffalo is, if the buffalo in question is a metaphor for taking advantage of opportunity, the band does just that.

The local indie-rock band is no stranger to success.

After winning Record Store Day High School Battle of the Bands in April 2010, which landed them a front-page spot on NUVO, an alternative newspaper in Indianapolis, the band recorded an album and was named Bloomington’s best local band that same year.   

After releasing their debut album “You, Me, and the Monster,” they shared the stage with several nationally known bands, including Dale Earnhardt Jr. Jr. and Margot & the Nuclear So & So’s.

But they’re not tired yet.

The band is currently among the top five bands competing in a contest for a spot to perform at South by Southwest Interactive Film and Music Festival in Austin, Texas, this March. The band found out about the contest on Sonicbids and submitted their song “Mountain Tiger.” The band members received an email two weeks ago informing them that they were finalists.

The Sonicbids-Jansport Battle of the Bands contest uses an online voting system to decide which 10 acts will be considered for the final round. Fans of the band are able to vote online once a day through Jan. 19. The top 10 acts will then be judged by a panel, which will announce the winner sometime in February.

“We’ve been playing on a local, slightly regional level for years together, and SXSW is the opportunity for us that is very attainable and would be the boost we need to have new people hear our music,” Kissinger said.

Are they nervous?

“You could say we’re a bunch of nervous nematodes,” Kissinger said.

According to Kissinger, their album “You, Me, and the Monster” has to do with hemorrhoids, or in their words, “pains in the ass.”

Examples of pains include skeletons, dirty dishes, women, drugs, money and paparazzi.

Not all of the band’s songs fall under these categories, though.

“Our song ‘Mountain Tiger’ is about a fight between a fierce tiger and a mean machine ... on a mountain,” sophomore bassist Marcus Tedesco said.

Tedesco met singer and guitarist Oliver Hopkins outside Read Center last year and has been part of the band ever since.

Following the success of their debut album, the band is starting to record a new album this month. The album includes tracks such as “Hay, is that My Horse?” and “Gallop Pasture Sister’s Head.”

“The second album will be a concept record based around the times and adventures of ‘Butch Cassidy and the Sundance Kid.’ It’ll be louder and dustier than record number one,” Hopkins said.

The title of the second album and when it will be out is still unknown.

“Maybe in a few months, maybe a year,” Hopkins said.

2011年9月15日星期四

What are hemorrhoids?

A precise definition of hemorrhoids does not exist, but they can be described as masses or clumps ("cushions") of tissue within the anal canal that contain blood vessels and the surrounding, supporting tissue made up of muscle and elastic fibers. The anal canal is the last four centimeters through which stool passes as it goes from the rectum to the outside world. The anus is the opening of the anal canal to the outside world.

Although most people think hemorrhoids are abnormal, they are present in everyone. It is only when the hemorrhoidal cushions enlarge that hemorrhoids can cause problems and be considered abnormal or a disease.

Although hemorrhoids occur in everyone, they become large and cause problems in only 4% of the general population. Hemorrhoids that cause problems are found equally in men and women, and their prevalence peaks between 45 and 65 years of age.

The arteries supplying blood to the anal canal descend into the canal from the rectum above and form a rich network of arteries that communicate with each other around the anal canal. Because of this rich network of arteries, hemorrhoidal blood vessels have a ready supply of arterial blood. This explains why bleeding from hemorrhoids is bright red (arterial blood) rather than dark red (venous blood), and why bleeding from hemorrhoids occasionally can be severe. The blood vessels that supply the hemorrhoidal vessels pass through the supporting tissue of the hemorrhoidal cushions.

The anal veins drain blood away from the anal canal and the hemorrhoids. These veins drain in two directions. The first direction is upwards into the rectum, and the second is downwards beneath the skin surrounding the anus. The dentate line is a line within the anal canal that denotes the transition from anal skin (anoderm) to the lining of the rectum.

Technically, the differentiation between internal and external hemorrhoids is made on the basis of whether the hemorrhoid originates above or below the dentate line (internal and external, respectively).

As discussed previously, hemorrhoidal cushions in the upper anal canal are made up of blood vessels and their supporting tissues. There usually are three major hemorrhoidal cushions oriented right posterior, right anterior, and left lateral. During the formation of enlarged internal hemorrhoids, the vessels of the anal cushions swell and the supporting tissues increase in size. The bulging mass of tissue and blood vessels protrudes into the anal canal where it can cause problems. Unlike with internal hemorrhoids, it is not clear how external hemorrhoids form.

2011年6月22日星期三

the Treatment of Moderate to Severe Pain Associated With Chronic Anal Fissures

ProStrakan Group plc, a subsidiary of Kyowa Hakko Kirin Co. Ltd., and an international specialty pharmaceutical company, today announces that it has received approval from the U.S. Food and Drug Administration (FDA) for Rectiv™ (nitroglycerin) Ointment 0.4 % for the treatment of moderate to severe pain associated with chronic anal fissures. Rectiv will be the only FDA approved prescription product for patients with this condition.

"The pain associated with anal fissures can be unrelenting and debilitating. Prompt initiation of treatment by primary care practitioners, gynecologists, gastroenterologists and surgeons alike is critical to a patient's wellbeing," said Scott Berry MD, FACS, colorectal surgeon and the principal investigator on one of Rectiv's clinical trials.

"Now we have an effective and easy-to-use topical ointment which allows grateful patients to resume their daily lives."

Anal fissures are fairly common, with approximately 700,000 people in the U.S. receiving a diagnosis or treatment for an episode each year. An anal fissure is a small tear in the skin that lines the anus, and can occur in a number of ways such as passing large or hard stools, straining during a bowel movement, or following an episode of diarrhea. When an anal fissure occurs, it typically causes severe pain and bleeding with bowel movements. Chronic anal fissure has been shown to impact significantly on patients' quality of life. An episode can take six to eight weeks to heal; and if healing does not occur then surgery may be required.(i -x)

Peter Allen, Chairman of ProStrakan, said:

"The market in the U.S. for a prescription medicine to treat chronic anal fissure pain is significant and, having successfully marketed this product in Europe for some years, we are pleased that it will now be made available to patients in the U.S."

"We will now evaluate the most efficient way of bringing this product to market and making it available as widely as is necessary."

ProStrakan expects Rectiv to be available in the U.S. in the first quarter of 2012. Marketed under the name Rectogesic®, the product is already approved in the EU and marketed by ProStrakan in all major European countries, where sales grew by 15% in 2010 to $14.4 million (9.3 million Pounds Sterling). The product has also been out-licensed outside Europe by ProStrakan to commercial partners in 34 countries worldwide.

2011年5月10日星期二

Waismann Method Medical Director Warns of Opioid-Induced Gastrointestinal Damage

Dr. Clifford A. Bernstein, co-medical director of The Waismann Method, an advanced procedure for rapid opiate detoxification under deep sedation, is warning Americans of the negative side effects to gastrointestinal health from sustained use of opioids. If used for a prolonged period of time, opioids are proven to cause significant damage to the gastrointestinal tract, including constipation, nausea, vomiting, spasms, formation of hard and dry stool, diverticulitis, and in severe cases colon rupture.

“Opioid medications commonly cause impaired gastrointestinal function after long-term use, which leads to a host of other uncomfortable and potentially life threatening issues,” said Bernstein. “Many people are unaware that opiate use can actually trigger these symptoms, and we believe it’s important for users, patients, and anyone close to them to be well-educated about these specific hazards of long-term use.”

According to Dr. Bernstein, people treated with opioids such as OxyContin, Percocet, and Vicodin, as well as maintenance therapies like methadone or Suboxone (both medications used to treat opioid addiction) for prolonged periods of time risk developing these physical issues. Most conditions stem from sluggish gastrointestinal function and constipation, which can cause users to strain during bowel movements, leading to painful hemorrhoids. Diverticulitis, an infection in the large intestines marked by the formation of pouches (diverticula) on the outside of the colon, can also occur from long-term use of these medications. This condition frequently causes abdominal pain, fever and bloating. If it progresses, diverticulitis can eventually cause colon rupture.

The Waismann Method of Opiate Detoxification is a pioneering medical procedure, which provides a safe and humane treatment for opiate dependency. Patients in the Waismann program are supervised closely in a hospital setting to maximize success and safety. All Waismann Method doctors are board certified in anesthesiology and pain management, and treatment is performed in the Intensive Care Unit of a hospital. Following detoxification, patients are transferred to Domus Retreat for mental and physical stabilization while under professional care.